*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : ES5615000
CHEMICAL NAME           : Butyric acid,
                          2-((2-(3-acetamido-2,4,6-triiodophenoxy)ethoxy)methyl
                          )-
CAS REGISTRY NUMBER     : 37723-78-7
BEILSTEIN REFERENCE NO. : 2782342
LAST UPDATED            : 199612
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C15-H18-I3-N-O5
MOLECULAR WEIGHT        : 673.04
WISWESSER LINE NOTATION : QVY2&1O2OR BI DI FI CMV1
COMPOUND DESCRIPTOR     : Drug
                          Reproductive Effector
SYNONYMS/TRADE NAMES :
   * 3-(2-(3-Acetylamino-2,4,6-triiodophenoxy)ethoxy)-2-ethylpropionic acid
   * 2-((2-(3-(Acetylamino)-2,4,6-triiodophenoxy)ethoxy)methyl)butanoic acid
   * B-11420
   * Bilimiro
   * Bilimiron
   * Butanoic acid,  
   2-((2-(3-(acetylamino)-2,4,6-triiodophenoxy)ethoxy)methyl)-
   * Iopronic acid
   * Oravue
   * SQ-21983
   * Videobil
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1090 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   43FLAV "Burger's Medicinal Chemistry," 4th ed., Wolff, M.E., ed., New York,
   John Wiley & Sons, Inc., 1980  Volume(issue)/page/year: 4(3),1153,1980
 
                          ** REPRODUCTIVE DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 3300 mg/kg
SEX/DURATION            : female 1-22 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Effects on Newborn - growth statistics (e.g.%, reduced weight
   gain)
REFERENCE :
   ATSUDG Archives of Toxicology, Supplement.  (Springer-Verlag New York, Inc.,
   Service Center, 44 Hartz Way, Secaucus, NJ 07094)  No.1-    1978-
   Volume(issue)/page/year: 7,425,1984
 
                            *** END OF RECORD ***