*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : EO5600000
CHEMICAL NAME           : t-Butylamine, N-methyl-N-nitroso-
CAS REGISTRY NUMBER     : 2504-18-9
BEILSTEIN REFERENCE NO. : 1922546
LAST UPDATED            : 199612
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C5-H12-N2-O
MOLECULAR WEIGHT        : 116.19
WISWESSER LINE NOTATION : ONN1&X1&1&1
COMPOUND DESCRIPTOR     : Mutagen
SYNONYMS/TRADE NAMES :
   * Methyl-tert-butylnitrosamine
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : >700 mg/kg
TOXIC EFFECTS :
   Lungs, Thorax, or Respiration - other changes
   Liver - other changes
REFERENCE :
   BIJOAK Biochemical Journal.  (Biochemical Soc. Book Depot, POB 32, Commerce
   Way, Colchester, Essex CO2 8HP, UK)  V.1-    1906- Volume(issue)/page/year:
   85,72,1962
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 630 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ZKKOBW Zeitschrift fuer Krebsforschung und Klinische Onkologie.  (Berlin,
   Fed. Rep. Ger.)  V.76-92, 1971-78.  For publisher information, see JCROD7.
   Volume(issue)/page/year: 80,17,1973

                          *** STATUS IN U.S. ***
 
   EPA GENETOX PROGRAM 1988, Negative: V79 cell culture-gene mutation

 
                            *** END OF RECORD ***