*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : EM9930000
CHEMICAL NAME           : 3-Buten-2-one, 1,1-diphenyl-4-piperidino-,
                          hydrochloride
CAS REGISTRY NUMBER     : 100482-64-2
LAST UPDATED            : 198806
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C21-H23-N-O.Cl-H
MOLECULAR WEIGHT        : 341.91
WISWESSER LINE NOTATION : T6NTJ A1V1UYR&R &GH
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 1,1-Diphenyl-4-piperidino-3-buten-2-one hydrochloride
   * Piperidino-4 diphenyl-1,1 butene-1 one-3 chlorhydrate
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 475 mg/kg
TOXIC EFFECTS :
   Brain and Coverings - recordings from specific areas of CNS
   Peripheral Nerve and Sensation - local anesthetic
   Behavioral - somnolence (general depressed activity)
REFERENCE :
   CHTPBA Chimica Therapeutica.  (Paris, France)  V.1-8, 1965-73.  For
   publisher information, see EJMCA5.  Volume(issue)/page/year: 1,35,1965
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 34 mg/kg
TOXIC EFFECTS :
   Brain and Coverings - recordings from specific areas of CNS
   Peripheral Nerve and Sensation - local anesthetic
   Behavioral - somnolence (general depressed activity)
REFERENCE :
   CHTPBA Chimica Therapeutica.  (Paris, France)  V.1-8, 1965-73.  For
   publisher information, see EJMCA5.  Volume(issue)/page/year: 1,35,1965
 
                            *** END OF RECORD ***