*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : EM8980000
CHEMICAL NAME           : 2-Butene, 1,1,1,2,3,4,4,4-octafluoro-
CAS REGISTRY NUMBER     : 360-89-4
BEILSTEIN REFERENCE NO. : 1783460
REFERENCE               : 4-01-00-00783 (Beilstein Handbook Reference)
LAST UPDATED            : 199710
DATA ITEMS CITED        : 6
MOLECULAR FORMULA       : C4-F8
MOLECULAR WEIGHT        : 200.04
WISWESSER LINE NOTATION : FXFFYFUYFXFFF
COMPOUND DESCRIPTOR     : Mutagen
SYNONYMS/TRADE NAMES :
   * 2-Butene, octafluoro-
   * FC-1318
   * Octafluorobutene-2
   * Perfluorobut-2-ene
   * Perfluoro-1-methylpropene
   * R 1318my
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LCLo - Lowest published lethal concentration
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 6100 ppm/4H
TOXIC EFFECTS :
   Behavioral - changes in motor activity (specific assay)
   Behavioral - tetany
   Nutritional and Gross Metabolic - weight loss or decreased weight gain
REFERENCE :
   DUPON* E.I. Dupont de Nemours and Company, Technical Sheet.  (1007 Market
   St., Wilmington, DE 19898)  Volume(issue)/page/year: 25JUL1967
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : Sex chromosome loss and nondisjunction
ROUTE OF EXPOSURE       : Inhalation
TEST SYSTEM             : Insect - Drosophila melanogaster
DOSE/DURATION           : 99 pph/10M
REFERENCE :
   ENVRAL Environmental Research.  (Academic Press, Inc., 1 E. First St.,
   Duluth, MN 55802) V.1-    1967-  Volume(issue)/page/year: 7,275,1974

         *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
   NOHS - National Occupational Hazard Survey (1974)
     NOHS Hazard Code - 81923
       No. of Facilities: 11 (estimated)
       No. of Industries: 1
       No. of Occupations: 3
       No. of Employees: 357 (estimated)

                          *** STATUS IN U.S. ***
 
   EPA GENETOX PROGRAM 1988, Inconclusive: D melanogaster Sex-linked lethal
   
   EPA TSCA Section 8(b) CHEMICAL INVENTORY
   
   EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JUNE 1998

 
                            *** END OF RECORD ***