*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : EM4910000
CHEMICAL NAME           : 2-Butene, 2,3-dichlorohexafluoro-
CAS REGISTRY NUMBER     : 303-04-8
LAST UPDATED            : 199806
DATA ITEMS CITED        : 5
MOLECULAR FORMULA       : C4-Cl2-F6
MOLECULAR WEIGHT        : 232.94
WISWESSER LINE NOTATION : FXFFYGUYGXFFF
SYNONYMS/TRADE NAMES :
   * 2-Butene, 2,3-dichloro-1,1,1,4,4,4-hexafluoro-
   * CFC 1316
   * CFC 1316 mxx
   * Dchfb
   * 2,3-Dichlorohexafluorobutene-2
   * 2,3-Dichloro-1,1,1,4,4,4-hexafluorobutene-2
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 1 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   DOWCC* Dow Chemical Company Reports.  (Dow Chemical USA, Health and
   Environment Research, Toxicology Research Lab., Midland, MI 48640)
   Volume(issue)/page/year: -,-,1963
 
TYPE OF TEST            : LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 16 ppm/4H
TOXIC EFFECTS :
   Behavioral - general anesthetic
   Lungs, Thorax, or Respiration - dyspnea
   Lungs, Thorax, or Respiration - cyanosis
REFERENCE :
   BJANAD British Journal of Anesthesia.  (Macmillan Press Ltd., Houndmills,
   Basingstoke, Hants. RG21 2XS, UK)  V.1-    1923-  Volume(issue)/page/year:
   37,716,1965
 
TYPE OF TEST            : LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 26 ppm/4H
TOXIC EFFECTS :
   Behavioral - general anesthetic
   Lungs, Thorax, or Respiration - dyspnea
   Lungs, Thorax, or Respiration - cyanosis
REFERENCE :
   BJANAD British Journal of Anesthesia.  (Macmillan Press Ltd., Houndmills,
   Basingstoke, Hants. RG21 2XS, UK)  V.1-    1923-  Volume(issue)/page/year:
   37,716,1965
 
TYPE OF TEST            : LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Mammal - dog
DOSE/DURATION           : 182 ppm/4H
TOXIC EFFECTS :
   Lungs, Thorax, or Respiration - fibrosis, focal (pneumoconiosis)
   Lungs, Thorax, or Respiration - acute pulmonary edema
REFERENCE :
   JETOAS Journal Europeen de Toxicologie.  (Paris, France)  V.1-6, 1968-72.
   For publisher information, see TOERD9.  Volume(issue)/page/year: 4,517,1971
 
TYPE OF TEST            : LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Primate - monkey
DOSE/DURATION           : 54 ppm/3H
TOXIC EFFECTS :
   Behavioral - ataxia
   Lungs, Thorax, or Respiration - changes in pulmonary vascular resistance
   Lungs, Thorax, or Respiration - consolidation
REFERENCE :
   ANESAV Anesthesiology.  (Lippincott/Harper, Journal Fulfillment Dept., 2350
   Virginia Ave., Hagerstown, MD 21740)  V.1-    1940- Volume(issue)/page/year:
   26,140,1965
 
                            *** END OF RECORD ***