*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : EL9190000
CHEMICAL NAME           : 1-Butanone,
                          1-(10-(3-(4-methyl-1-piperazinyl)propyl)phenothiazin-
                          2-yl)-
CAS REGISTRY NUMBER     : 653-03-2
LAST UPDATED            : 199007
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C24-H31-N3-O-S
MOLECULAR WEIGHT        : 409.64
WISWESSER LINE NOTATION : T C666 BN ISJ B3- AT6N DNTJ D1& MV3
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * AHR-712
   * Bayer 1362
   * 1-Butanone,  
   1-(10-(3-(4-methyl-1-piperazinyl)propyl)-10H-phenothiazin-2-yl)-
   * Butaperazine
   * 3-n-Butyryl-10-(3'-N-methyl-piperazino-N'-propyl)phenothiazin
   * Butyrylperazine
   * Emerex
   * Megalectil
   * 1-(10-(3-(4-Methyl-1-piperazinyl)propyl)phenothiazin-2-yl)-1-butanone
   * Randolectil
   * Repoise
   * Riker 595
   * Tyrylen
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 413 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   19,93,1971
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 67 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
REFERENCE :
   AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
   Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium)  V.4-   
   1898-  Volume(issue)/page/year: 115,1,1958
 
                            *** END OF RECORD ***