*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : EL7880000
CHEMICAL NAME           : 1-Butanone,
                          1-(10-(3-(dimethylamino)propyl)phenothiazin-2-yl)-
CAS REGISTRY NUMBER     : 20769-36-2
LAST UPDATED            : 198910
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C21-H26-N2-O-S
MOLECULAR WEIGHT        : 354.55
WISWESSER LINE NOTATION : T C666 BN ISJ B3N1&1 MV3
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 1-Butanone, 1-(10-(3-(dimethylamino)propyl)-10H-phenothiazin-2-yl)-
   * 3-n-Butyryl-10-(3'-dimethylaminopropyl)phenothiazine
   * 3-Butylryl-promazin
   * Butyrylpromazine
   * 3-Butyrylpromazine
   * 1-(10-(3-(Dimethylamino)propyl)phenothiazin-2-yl)-1-butanone
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 300 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
REFERENCE :
   AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
   Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium)  V.4-   
   1898-  Volume(issue)/page/year: 115,1,1958
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 73 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
REFERENCE :
   AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
   Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium)  V.4-   
   1898-  Volume(issue)/page/year: 115,1,1958
 
                            *** END OF RECORD ***