*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : EL6506666
CHEMICAL NAME           : 1-Butanone,
                          4-(4-acetyl-4-(3-methoxyphenyl)-1-piperidinyl)-1-(4-f
                          luorophenyl)-
LAST UPDATED            : 199703
DATA ITEMS CITED        : 4
MOLECULAR FORMULA       : C24-H28-F-N-O3
MOLECULAR WEIGHT        : 397.53
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   *   4-(4-Acetyl-4-(3-methoxyphenyl)-1-piperidinyl)-1-(4-fluorophenyl)-1-buta
     none
   * Butyrophenone, 4-(4-acetyl-4-(m-methoxyphenyl)piperidino)-4'-fluoro-
   *   1-(4'-Oxo-4-(p-fluorophenyl)-n-butyl-1')-4-acetyl-4-(m-methoxyphenyl)-pi
     peridine
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 300 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   USXXAM United States Patent Document.  (U.S. Patent Office, Box 9,
   Washington, DC 20231)  Volume(issue)/page/year: #3689492
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 380 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   USXXAM United States Patent Document.  (U.S. Patent Office, Box 9,
   Washington, DC 20231)  Volume(issue)/page/year: #3689492
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Mammal - dog
DOSE/DURATION           : 338 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   USXXAM United States Patent Document.  (U.S. Patent Office, Box 9,
   Washington, DC 20231)  Volume(issue)/page/year: #3689492
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Mammal - dog
DOSE/DURATION           : 80 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   USXXAM United States Patent Document.  (U.S. Patent Office, Box 9,
   Washington, DC 20231)  Volume(issue)/page/year: #3689492
 
                            *** END OF RECORD ***