*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : EK8156000
CHEMICAL NAME           : Butanoic acid,
                          3-oxo-2-((4-oxo-3(4H)-quinazolinyl)methyl)-, ethyl
                          ester, dihydrochloride
CAS REGISTRY NUMBER     : 75159-44-3
LAST UPDATED            : 199212
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C15-H16-N2-O4.2Cl-H
MOLECULAR WEIGHT        : 361.25
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Ethyl 3-oxo-2-((4-oxo-3(4H)-quinazolinyl)methyl)butanoate dihydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 400 mg/kg
TOXIC EFFECTS :
   Brain and Coverings - recordings from specific areas of CNS
   Behavioral - somnolence (general depressed activity)
   Behavioral - ataxia
REFERENCE :
   JICSAH Journal of the Indian Chemical Society.  (Indian Chemical Soc., 92,
   Acharya Prafulla Chandra Rd., Calcutta 700009, India)  V.5-     1928-
   Volume(issue)/page/year: 56,1226,1979
 
                            *** END OF RECORD ***