*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : EK7789900
CHEMICAL NAME           : Butanoic acid, 2,3-dihydroxy-2-(1-methylethyl)-,
                          (2,3,5,7a-tetrahydro-1-hydroxy-1H-pyrrolizin-7-yl)met
                          hyl ester, (1R-(1a,7(2R*,3S*),7a-beta))-
CAS REGISTRY NUMBER     : 480-82-0
BEILSTEIN REFERENCE NO. : 4324630
LAST UPDATED            : 199709
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C15-H25-N-O5
MOLECULAR WEIGHT        : 299.41
SYNONYMS/TRADE NAMES :
   * Indicine
   * (+)-Indicine
 
                       *** HEALTH HAZARD DATA ***
 
                 ** OTHER MULTIPLE DOSE TOXICITY DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 40 gm/kg/4W-I
TOXIC EFFECTS :
   Liver - hepatitis (hepatocellular necrosis), zonal
   Blood - macrocytosis
   Related to Chronic Data - death
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   101,271,1989
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1350 mg/kg/9D-I
TOXIC EFFECTS :
   Blood - macrocytosis
   Related to Chronic Data - death
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   101,271,1989
 
                            *** END OF RECORD ***