*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : EK3150000
CHEMICAL NAME           : 2,3-Butanedione, monooxime
CAS REGISTRY NUMBER     : 57-71-6
BEILSTEIN REFERENCE NO. : 0605582
REFERENCE               : 4-01-00-03646 (Beilstein Handbook Reference)
LAST UPDATED            : 199701
DATA ITEMS CITED        : 6
MOLECULAR FORMULA       : C4-H7-N-O2
MOLECULAR WEIGHT        : 101.12
WISWESSER LINE NOTATION : QNUY1&V1
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Biacetylmonoxime
   * 2,3-Butanedione 2-oxime
   * DAM
   * Diacetylmonooxime
   * Diacetylmonoxime
   * 2-Oximino-3-butanone
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 51 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JPMSAE Journal of Pharmaceutical Sciences.  (American Pharmaceutical Assoc.,
   2215 Constitution Ave., NW, Washington, DC 20037)  V.50-    1961-
   Volume(issue)/page/year: 53,1143,1964
 
                 ** OTHER MULTIPLE DOSE TOXICITY DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 6850 mg/kg/23D-I
TOXIC EFFECTS :
   Gastrointestinal - hypermotility, diarrhea
   Gastrointestinal - other changes
   Nutritional and Gross Metabolic - weight loss or decreased weight gain
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 119,522,1957

                              *** REVIEWS ***
 
   TOXICOLOGY REVIEW
   JPMSAE Journal of Pharmaceutical Sciences.  (American Pharmaceutical Assoc.,
   2215 Constitution Ave., NW, Washington, DC 20037)  V.50-    1961-
   Volume(issue)/page/year: 53,1143,1964

         *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
   NOHS - National Occupational Hazard Survey (1974)
     NOHS Hazard Code - M0440
       No. of Facilities: 718 (estimated)
       No. of Industries: 1
       No. of Occupations: 3
       No. of Employees: 4820 (estimated)
   
   NOES - National Occupational Exposure Survey (1983)
     NOES Hazard Code - M0440
       No. of Facilities: 370 (estimated)
       No. of Industries: 2
       No. of Occupations: 5
       No. of Employees: 1974 (estimated)
       No. of Female Employees: 1730 (estimated)

                          *** STATUS IN U.S. ***
 
   EPA TSCA Section 8(b) CHEMICAL INVENTORY

 
                            *** END OF RECORD ***