*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : EJ9854000
CHEMICAL NAME           : Butanedioic acid, compd. with
                          4-(2-chloro-10,11-dihydrodibenzo(b,f)thiepin-10-yl)-1
                          - piperazineethanol
CAS REGISTRY NUMBER     : 60003-04-5
OTHER CAS REGISTRY NOS. : 64756-08-7
LAST UPDATED            : 199304
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C20-H23-Cl-N2-O-S.xC4-H6-O4
MOLECULAR WEIGHT        : 1201.66
COMPOUND DESCRIPTOR     : Drug
                          Mutagen
SYNONYMS/TRADE NAMES :
   * 4-(2-Chloro-10,11-dihydrodibenzo(b,f)thiepin-10-yl)-1-piperazineethanol  
   succinate
   *   2-Chloro-10-(4-(2-hydroxyethyl)piperazino)-10,11-dihydrodibenzo(b,f)thie
     pin succinate
   * Dibenzo(b,f)thiepin, 1-piperazineethanol deriv.
   * Docloxythepin succinate
   * Dokloxythepin succinate
   * VUFB10032
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 84 mg/kg
TOXIC EFFECTS :
   Behavioral - ataxia
REFERENCE :
   CCCCAK Collection of Czechoslovak Chemical Communications.  (Academic Press
   Inc. Ltd., 24-28 Oval Rd., London NW1 7DX, UK)  V.1-    1929-
   Volume(issue)/page/year: 44,3008,1979

                          *** STATUS IN U.S. ***
 
   EPA GENETOX PROGRAM 1988, Negative: Rodent dominant lethal

 
                            *** END OF RECORD ***