*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : EF8750000
CHEMICAL NAME           : Bromic acid, sodium salt
CAS REGISTRY NUMBER     : 7789-38-0
LAST UPDATED            : 199712
DATA ITEMS CITED        : 8
MOLECULAR FORMULA       : Br-O3.Na
MOLECULAR WEIGHT        : 150.90
WISWESSER LINE NOTATION :  NA  E-O3
COMPOUND DESCRIPTOR     : Tumorigen
SYNONYMS/TRADE NAMES :
   * Bromate de sodium
   * Dyetone
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 140 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   COREAF Comptes Rendus Hebdomadaires des Seances, Academie des Sciences.
   (Paris, France)  V.1-261, 1835-1965.  For publisher information, see CRASEV.
    Volume(issue)/page/year: 257,791,1963
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Mammal - dog
DOSE/DURATION           : 120 mg/kg
TOXIC EFFECTS :
   Behavioral - muscle weakness
   Lungs, Thorax, or Respiration - respiratory depression
   Blood - other changes
REFERENCE :
   SAPHAO Skandinavisches Archiv fuer Physiologie.  (Stockholm, Sweden) V.1-83,
   1899-1940.  For publisher information, see APSCAX. Volume(issue)/page/year:
   30,337,1913
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 250 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Gastrointestinal - hypermotility, diarrhea
   Blood - other changes
REFERENCE :
   SAPHAO Skandinavisches Archiv fuer Physiologie.  (Stockholm, Sweden) V.1-83,
   1899-1940.  For publisher information, see APSCAX. Volume(issue)/page/year:
   30,337,1913
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 360 mg/kg
TOXIC EFFECTS :
   Lungs, Thorax, or Respiration - dyspnea
   Gastrointestinal - hypermotility, diarrhea
   Blood - other changes
REFERENCE :
   SAPHAO Skandinavisches Archiv fuer Physiologie.  (Stockholm, Sweden) V.1-83,
   1899-1940.  For publisher information, see APSCAX. Volume(issue)/page/year:
   30,337,1913
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - guinea pig
DOSE/DURATION           : 100 mg/kg
TOXIC EFFECTS :
   Lungs, Thorax, or Respiration - respiratory depression
   Kidney, Ureter, Bladder - hematuria
   Blood - other changes
REFERENCE :
   SAPHAO Skandinavisches Archiv fuer Physiologie.  (Stockholm, Sweden) V.1-83,
   1899-1940.  For publisher information, see APSCAX. Volume(issue)/page/year:
   30,337,1913

         *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
   NOES - National Occupational Exposure Survey (1983)
     NOES Hazard Code - X4132
       No. of Facilities: 2680 (estimated)
       No. of Industries: 5
       No. of Occupations: 9
       No. of Employees: 27921 (estimated)
       No. of Female Employees: 18633 (estimated)

                          *** STATUS IN U.S. ***
 
   EPA TSCA Section 8(b) CHEMICAL INVENTORY
   
   NTP Carcinogenesis studies; selected, October 1997

 
                            *** END OF RECORD ***