*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : DT4200000
CHEMICAL NAME           : 2,5'-Bibenzimidazole,
                          2'-(p-ethoxyphenyl)-5-(4-methyl-1-piperazinyl)-
CAS REGISTRY NUMBER     : 23491-52-3
LAST UPDATED            : 199312
DATA ITEMS CITED        : 4
COMPOUND DESCRIPTOR     : Mutagen
SYNONYMS/TRADE NAMES :
   * 2,5'-Bi-1H-benzimidazole, 2'-(4-ethoxyphenyl)-5-(4-methyl-1-piperazinyl)-
   * HOE 33342
   * Hoechst 33342
 
                       *** HEALTH HAZARD DATA ***
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : DNA inhibition
TEST SYSTEM             : Human HeLa cell
DOSE/DURATION           : 300 nmol/L
REFERENCE :
   CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House,
   Southfield Road, Eynsham, Oxford OX8 1JJ, UK)  V.1-    1980-
   Volume(issue)/page/year: 13,2389,1992
 
TYPE OF TEST            : DNA damage
TEST SYSTEM             : Rodent - mouse Fibroblast
DOSE/DURATION           : 5 umol/L
REFERENCE :
   CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House,
   Southfield Road, Eynsham, Oxford OX8 1JJ, UK)  V.1-    1980-
   Volume(issue)/page/year: 9,485,1988
 
TYPE OF TEST            : DNA damage
TEST SYSTEM             : Rodent - hamster Lung
DOSE/DURATION           : 1 umol/L
REFERENCE :
   JHCYAS Journal of Histochemistry and Cytochemistry.  (Elsevier Science Pub.
   Co., Inc., 52 Vanderbilt Ave., New York, NY 10017)  V.1-    1953-
   Volume(issue)/page/year: 30,111,1982
 
TYPE OF TEST            : DNA inhibition
TEST SYSTEM             : Rodent - hamster Lung
DOSE/DURATION           : 1 umol/L
REFERENCE :
   JHCYAS Journal of Histochemistry and Cytochemistry.  (Elsevier Science Pub.
   Co., Inc., 52 Vanderbilt Ave., New York, NY 10017)  V.1-    1953-
   Volume(issue)/page/year: 30,111,1982
 
                            *** END OF RECORD ***