*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : DU1780000
CHEMICAL NAME           : Biguanide, 1-(m-chlorophenyl)-, monohydrochloride
CAS REGISTRY NUMBER     : 2113-05-5
LAST UPDATED            : 199007
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C8-H10-Cl-N5.Cl-H
MOLECULAR WEIGHT        : 248.14
WISWESSER LINE NOTATION : MUYZMYUM&MR CG &GH
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * N-m-Chlorophenylbiguanide hydrochloride
   * 1-(m-Chlorophenyl)biguanide hydrochloride
   * N-(3-Chlorophenyl)-imidodicarbonimidic diamide monohydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 186 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 10,521,1967
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 350 mg/kg
TOXIC EFFECTS :
   Endocrine - hyperglycemia
REFERENCE :
   IJOCAP Indian Journal of Chemistry.  (New Delhi, India)  V.1-13, 1963-75.
   Divided into Indian Journal of Chemistry, Section A and Indian Journal of
   Chemistry, Section B.  Volume(issue)/page/year: 1,218,1962
 
                            *** END OF RECORD ***