*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : DT8060000
CHEMICAL NAME           : Bicyclo(4.2.0)oct-4-en-3-one,
                          6-hydroxy-8-isocyano-8-(1-isocyano-2-(4-methoxyphenyl
                          )ethenyl)-
CAS REGISTRY NUMBER     : 123949-57-5
LAST UPDATED            : 199209
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C19-H16-N2-O3
MOLECULAR WEIGHT        : 320.37
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Antibiotic MK4588
   * Leptocillin
   * (+)-Leptocillin
   * MK4588
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >40 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JANTAJ Journal of Antibiotics.  (Japan Antibiotics Research Assoc., 2-20-8
   Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan)  V.2-5, 1948-52;  V.21- 1968-
   Volume(issue)/page/year: 43,456,1990
 
                            *** END OF RECORD ***