*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : DM5314746
CHEMICAL NAME           : (1)Benzoxepino(3,4-b)pyridin-5-amine,
                          5,11-dihydro-N-(2-(1-pyrrolidinyl)ethyl)-,
                          hydrochloride, hydrate (2:6:1)
CAS REGISTRY NUMBER     : 95968-77-7
LAST UPDATED            : 199612
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C19-H23-N3-O.3Cl-H.1/2H2-O
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   *   5-(2-(1-Pyrrolidinyl)ethyl)amino-5,11-dihydro-(1)benzoxepino(3,4-b)pyrid
     ine 3HCl hemihydrate
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD - Lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >300 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   EPXXDW European Patent Application. (U.S. Patent and Trademark Office,
   Foreign Patents, Washington, DC 20231)  Volume(issue)/page/year: #0129879
 
TYPE OF TEST            : LD - Lethal dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >100 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   EPXXDW European Patent Application. (U.S. Patent and Trademark Office,
   Foreign Patents, Washington, DC 20231)  Volume(issue)/page/year: #0129879
 
                            *** END OF RECORD ***