*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : DO8720000
CHEMICAL NAME           : Benzyl alcohol,
                          alpha-((isopropylamino)methyl)-p-nitro-,
                          monohydrochloride, (+-)-
CAS REGISTRY NUMBER     : 5704-60-9
LAST UPDATED            : 199706
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C11-H16-N2-O3.Cl-H
MOLECULAR WEIGHT        : 260.75
WISWESSER LINE NOTATION : WNR DYQ1MY1&1 &GH
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Benzenemethanol, alpha-(((1-methylethyl)amino)methyl)-4-nitro-,  
   monohydrochloride, (+-)-
   * INPEA
   * (+-)-INPEA hydrochloride
   * dl-INPEA hydrochloride
   * DL-INPEA hydrochloride
   * (+-)-2-(Isopropylamino)-1-(p-nitrophenyl)ethanol hydrochloride
   * Nifenalol hydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 186 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - ataxia
   Lungs, Thorax, or Respiration - respiratory stimulation
REFERENCE :
   IJPPAZ Indian Journal of Physiology and Pharmacology.  (All India Institute
   of Medical Sciences, Dept. of Physiology, Ansari Nagar, New Delhi 110 029,
   India)  V.1-    1957-  Volume(issue)/page/year: 17,235,1973
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 70 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 27,1022,1977
 
                            *** END OF RECORD ***