*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : DO7700000
CHEMICAL NAME           : Benzyl alcohol,
                          p-hydroxy-alpha-((methylamino)methyl)-, hydrochloride
CAS REGISTRY NUMBER     : 5985-28-4
LAST UPDATED            : 199712
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C9-H13-N-O2.Cl-H
MOLECULAR WEIGHT        : 203.69
WISWESSER LINE NOTATION : QR DYQ1M1 &GH
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Benzenemethanol, 4-hydroxy-alpha-((methylamino)methyl)-, hydrochloride
   * p-Hydroxy-alpha-(methylaminomethyl)benzyl alcohol hydrochloride
   * l-1-p-Hydroxyphenyl-2-methylamino-1-ethanol hydrochloride
   * p-Methylaminoaethanolphenol hydrochlorid
   * p-Methylaminoethanol phenol hydrochloride
   * Synephrine hydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 320 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 71,62,1941
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 400 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AEPPAE Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und
   Pharmakologie.  (Berlin, Ger.) V.110-253, 1925-66.  For publisher
   information, see NSAPCC.  Volume(issue)/page/year: 124,231,1927
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - guinea pig
DOSE/DURATION           : 500 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AEPPAE Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und
   Pharmakologie.  (Berlin, Ger.) V.110-253, 1925-66.  For publisher
   information, see NSAPCC.  Volume(issue)/page/year: 124,231,1927
 
                            *** END OF RECORD ***