*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : DO7350000
CHEMICAL NAME           : Benzyl alcohol,
                          p-hydroxy-alpha-((methylamino)methyl)-
CAS REGISTRY NUMBER     : 94-07-5
LAST UPDATED            : 199601
DATA ITEMS CITED        : 5
MOLECULAR FORMULA       : C9-H13-N-O2
MOLECULAR WEIGHT        : 167.23
WISWESSER LINE NOTATION : QR DYQ1M1
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Analeptin
   * Ethaphene
   * 4-Hydroxy-alpha-((methylamino)methyl)benzenemethanol
   * p-Hydroxy-alpha-((methylamino)methyl)benzyl alcohol
   * p-Hydroxyphenylmethylaminoethanol
   * 1-(4-Hydroxyphenyl)-2-methylaminoethanol
   * 1-(4-Hydroxyphenyl)-N-methylethanolamine
   * p-Methylaminoethanolphenol
   * beta-Methylamino-alpha-(4-hydroxyphenyl)ethyl alcohol
   * Methylaminomethyl(4-hydroxyphenyl)carbinol
   * Oxedrine
   * p-Oxedrine
   * alpha-(4-Oxyphenyl)alpha-oxy-beta-methylaminoaethan
   * Parakorper
   * Parasympatol
   * Pentedrin
   * S 38537-9
   * Simpalon
   * Simpatol
   * Sympathol
   * Synefrin
   * Synephrin
   * Synephrine
   * p-Synephrine
   * Synthenate
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 1500 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
   Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium)  V.4-   
   1898-  Volume(issue)/page/year: 101,81,1955
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 89,297,1947
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1500 mg/kg
TOXIC EFFECTS :
   Sense Organs and Special Senses (Eye) - effect, not otherwise specified
   Behavioral - convulsions or effect on seizure threshold
   Lungs, Thorax, or Respiration - respiratory stimulation
REFERENCE :
   AEPPAE Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und
   Pharmakologie.  (Berlin, Ger.) V.110-253, 1925-66.  For publisher
   information, see NSAPCC.  Volume(issue)/page/year: 136,172,1928
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 270 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 106,341,1952
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 150 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
   Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium)  V.4-   
   1898-  Volume(issue)/page/year: 101,81,1955
 
                            *** END OF RECORD ***