*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : DO2300200
CHEMICAL NAME           : Benzyl alcohol,
                          3,4-dihydroxy-alpha-((isopropylamino)methyl)-, (+)-,
                          (+)-tartrate (1:1) (salt)
CAS REGISTRY NUMBER     : 14638-70-1
LAST UPDATED            : 198903
DATA ITEMS CITED        : 4
MOLECULAR FORMULA       : C11-H17-N-O3.C4-H6-O6
MOLECULAR WEIGHT        : 361.39
WISWESSER LINE NOTATION : QR BQ DYQ1MY1&1 &QVYQYQVQ -D -D
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * (+)-Isoprenaline bitartrate
   * d-N-Isopropylnorepinephrine bitartrate
   * (+)-Isoproterenol bitartrate
   * d-Isoproterenol bitartrate
   * L-(+)-Isoproterenol bitartrate
   * (S)-Isoproterenol bitartrate
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 183 mg/kg
TOXIC EFFECTS :
   Cardiac - other changes
   Lungs, Thorax, or Respiration - other changes
REFERENCE :
   AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
   Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium)  V.4-   
   1898-  Volume(issue)/page/year: 137,155,1962
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 4504 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   SCPHA4 Scientia Pharmaceutica.  (Oesterreichische
   Apotheker-Verlagsgesellschaft MBH, Spitalgasse 31, 1094 Vienna 9, Austria)
   V.1-    1930-  Volume(issue)/page/year: 21,1,1953
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1844 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   SCPHA4 Scientia Pharmaceutica.  (Oesterreichische
   Apotheker-Verlagsgesellschaft MBH, Spitalgasse 31, 1094 Vienna 9, Austria)
   V.1-    1930-  Volume(issue)/page/year: 21,1,1953
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 101 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 111,469,1954
 
                            *** END OF RECORD ***