*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : DO0350000
CHEMICAL NAME           : Benzyl alcohol,
                          alpha-(1-(N-cinnamyl-N-methylamino)ethyl)-,
                          hydrochloride, (+)-
CAS REGISTRY NUMBER     : 64043-53-4
LAST UPDATED            : 199010
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C19-H23-N-O.Cl-H
MOLECULAR WEIGHT        : 317.89
WISWESSER LINE NOTATION : QYR&Y1&N1&2U1R &GH
COMPOUND DESCRIPTOR     : Human
SYNONYMS/TRADE NAMES :
   * d-Cinnamylephedrine hydrochloride
   * Cinnamylephedrine hydrochloride, dextro
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intradermal
SPECIES OBSERVED        : Human
DOSE/DURATION           : 143 ng/kg
TOXIC EFFECTS :
   Peripheral Nerve and Sensation - local anesthetic
   Skin and Appendages - corrosive (after topical exposure)
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 76,295,1942
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 75 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - excitement
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 76,295,1942
 
                            *** END OF RECORD ***