*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : DM4675250
CHEMICAL NAME           : 4-Benzoxazolecarboxylic acid,
                          2-((3,9-dimethyl-8-(1-methyl-2-oxo-2-(1H-pyrrol-2-yl)
                          ethyl)-1,7-dioxaspiro
                          (5.5)undec-2-yl)methyl)-5-hydroxy-, monosodium salt,
                          hydrate (2R-(2-alpha,3- alpha,6-beta),8S*(S*),9R*)-
CAS REGISTRY NUMBER     : 83874-20-8
LAST UPDATED            : 199306
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C27-H31-N2-O7.Na.H2-O
MOLECULAR WEIGHT        : 536.61
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Antibiotic X 14885A sodium salt hydrate
   *   2-(3-Hydroxy-2-(((3-hydroxy-2-pyridinyl)carbonyl)amino)phenyl)-4-benzoxa
     zolecarboxylic acid
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >1 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JANTAJ Journal of Antibiotics.  (Japan Antibiotics Research Assoc., 2-20-8
   Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan)  V.2-5, 1948-52;  V.21- 1968-
   Volume(issue)/page/year: 37,84-156,1984
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 65 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JANTAJ Journal of Antibiotics.  (Japan Antibiotics Research Assoc., 2-20-8
   Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan)  V.2-5, 1948-52;  V.21- 1968-
   Volume(issue)/page/year: 37,84-156,1984
 
                            *** END OF RECORD ***