*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : DM4472500
CHEMICAL NAME           : 5-Benzoxazoleacetic acid,
                          2-(4-fluorophenyl)-alpha-methyl-, (S)-
CAS REGISTRY NUMBER     : 66934-18-7
BEILSTEIN REFERENCE NO. : 1085079
LAST UPDATED            : 199612
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C16-H12-F-N-O3
MOLECULAR WEIGHT        : 285.29
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Flunoxaprofen
   * (+)-Flunoxaprofen
   * (S)-(+)-Flunoxaprofen
   * Flunoxaprofeno
   * (S)-2-(4-Fluorophenyl)-alpha-methyl-5-benzoxazoleacetic acid
   * Priaxim
   * RV-12424
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 521 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   DRFUD4 Drugs of the Future.  (J.R. Prous, S.A., Apartado de Correos 540,
   08080 Barcelona, Spain) V.1-    1975/76-  Volume(issue)/page/year:
   11,187,1986
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1275 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   DRFUD4 Drugs of the Future.  (J.R. Prous, S.A., Apartado de Correos 540,
   08080 Barcelona, Spain) V.1-    1975/76-  Volume(issue)/page/year:
   11,187,1986
 
                            *** END OF RECORD ***