*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : DM3858310
CHEMICAL NAME           : 2H-1,4-Benzoxazin-3(4H)-one, hexahydro-8a-phenyl-,
                          trans-
CAS REGISTRY NUMBER     : 89263-12-7
LAST UPDATED            : 199406
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C14-H17-N-O2
MOLECULAR WEIGHT        : 231.32
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * trans-Hexahydro-8a-phenyl-2H-1,4-benzoxazin-3(4H)-one
   * trans-1-Phenyl-2-oxa-5-azabicyclo(4.4.0)decan-4-one
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >800 mg/kg
TOXIC EFFECTS :
   Behavioral - altered sleep time (including change in righting reflex)
   Behavioral - changes in motor activity (specific assay)
REFERENCE :
   EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique.
   (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France)
   V.9-    1974-  Volume(issue)/page/year: 18,563,1983
 
                            *** END OF RECORD ***