*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : DM3325000
CHEMICAL NAME           : 2H-1,4-Benzoxazin-3-(4H)-one,
                          2,2-bis(p-hydroxyphenyl)-, diacetate
CAS REGISTRY NUMBER     : 14008-48-1
BEILSTEIN REFERENCE NO. : 0589169
LAST UPDATED            : 199612
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C24-H19-N-O6
MOLECULAR WEIGHT        : 417.44
WISWESSER LINE NOTATION : T66 BMV EO DHJ DR DOV1& DR DOV1
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 2H-1,4-Benzoazin-3(4H)-one, 2,2-bis(4-(acetoxy)phenyl)-
   * 2,2-Bis(4-acetoxyphenyl)-3-oxo-2,3-dihydrobenz-1,4-oxazine
   * 2,2-Bis(4-(acetyloxy)phenyl)-2H-1,4-benzoxazin-3(4H)-one diacetate
   * 2,2-Bis(p-hydroxyphenyl)-2H-1,4-benzoazin-3(4H)-one diacetate
   * Bisoxatin acetate
   * Laxonalin
   * Maratan
   * Talsis
   * Tasis
   * WY 8138
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 8 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NIIRDN Drugs in Japan (Ethical Drugs).  (Yakugyo Jiho Co., Ltd., Tokyo,
   Japan)  Volume(issue)/page/year: 6,609,1982
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 600 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   18,185,1971
 
                            *** END OF RECORD ***