*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : DM3160000
CHEMICAL NAME           : 2H-1,4-Benzoxazine, octahydro-4-methyl-8a-phenyl-,
                          (E)-
CAS REGISTRY NUMBER     : 89263-15-0
BEILSTEIN REFERENCE NO. : 5266504
LAST UPDATED            : 199612
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C15-H21-N-O
MOLECULAR WEIGHT        : 231.37
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * trans-4-Methyl-8a-phenyloctahydro-2H-1,4-benzoxazine
   * trans-1-Phenyl-5-methyl-2-oxa-5-azabicyclo(4.4.0)decane
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 600 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Nutritional and Gross Metabolic - body temperature decrease
REFERENCE :
   EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique.
   (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France)
   V.9-    1974-  Volume(issue)/page/year: 18,563,1983
 
                            *** END OF RECORD ***