*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : DM3078600
CHEMICAL NAME           : 2H-1,3-Benzoxazine,
                          3,4-dihydro-8-methoxy-6-methyl-3-(2-phenylethyl)-,
                          4-methylbenzenesulfonate (salt), hydrate (1:1:1)
LAST UPDATED            : 199109
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C18-H21-N-O2.C7-H8-O3-S.H2-O
MOLECULAR WEIGHT        : 473.63
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * FS-138
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >300 mg/kg
TOXIC EFFECTS :
   Sense Organs and Special Senses (Eye) - mydriasis (pupillary dilation)
   Sense Organs and Special Senses (Eye) - ptosis
   Nutritional and Gross Metabolic - body temperature decrease
REFERENCE :
   TAKHAA Takeda Kenkyusho Ho.  Journal of the Takeda Research Laboratories.
   (Takeda Yakuhin Kogyo K.K., 2-17-85 Jusohon-machi, Yodogawa-ku, Osaka 532,
   Japan)  V.29-    1970-  Volume(issue)/page/year: 34,455,1975
 
                            *** END OF RECORD ***