*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : DM3070000
CHEMICAL NAME           : 1H-2,3-Benzoxazine,
                          3,4-dihydro-7-chloro-3-(2-piperidinoethyl)-,
                          dihydrochloride
CAS REGISTRY NUMBER     : 21977-22-0
LAST UPDATED            : 199007
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C15-H21-Cl-N2-O.2Cl-H
MOLECULAR WEIGHT        : 353.75
WISWESSER LINE NOTATION : T66 CNOT&J HG C2- AT6NTJ &GH 2
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 1H-2,3-Benzoxazine, 7-chloro-3,4-dihydro-3-(2-piperidinoethyl)-,  
   dihydrochloride
   * 7-Chloro-3-(2-piperidinoethyl)-3,4-dihydro-1H-2,3-benzoxazine  
   dihydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 200 mg/kg
TOXIC EFFECTS :
   Behavioral - altered sleep time (including change in righting reflex)
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - ataxia
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 12,261,1969
 
                            *** END OF RECORD ***