*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : DM2980200
CHEMICAL NAME           : 2H-1,4-Benzoxazine-6-acetic acid, 3-(4-methylphenyl)-
CAS REGISTRY NUMBER     : 86818-28-2
BEILSTEIN REFERENCE NO. : 4509266
LAST UPDATED            : 199612
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C17-H15-N-O3
MOLECULAR WEIGHT        : 281.33
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 3-(4-Methylphenyl)-2H-1,4-benzoxazine-6-acetic acid
   * 3-p-Tolyl-2H-1,4-benzoxazine-6-acetic acid
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 316 mg/kg
TOXIC EFFECTS :
   Behavioral - changes in motor activity (specific assay)
   Kidney, Ureter, Bladder - urine volume increased
   Nutritional and Gross Metabolic - body temperature decrease
REFERENCE :
   IJSBDB Indian Journal of Chemistry, Section B: Organic Chemistry, Including
   Medicinal Chemistry. (Publications & Information Directorate, Council of
   Scientific and Industrial Research (CSIR), Hillside Rd., New Delhi 110 012,
   India)  V.14B-    1976-  Volume(issue)/page/year: 22,297,1983
 
                            *** END OF RECORD ***