*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : DM2979600
CHEMICAL NAME           : 2H-1,4-Benzoxazine-6-acetic acid,
                          3-(4-fluorophenyl)-2-oxo-, methyl ester
CAS REGISTRY NUMBER     : 78587-63-0
BEILSTEIN REFERENCE NO. : 4539779
LAST UPDATED            : 199612
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C17-H12-F-N-O4
MOLECULAR WEIGHT        : 313.30
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 3-(4-Fluorophenyl)-2-oxo-2H-1,4-benzoxazine-6-acetic acid methyl ester
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1 gm/kg
TOXIC EFFECTS :
   Brain and Coverings - recordings from specific areas of CNS
   Behavioral - somnolence (general depressed activity)
   Nutritional and Gross Metabolic - body temperature decrease
REFERENCE :
   IJSBDB Indian Journal of Chemistry, Section B: Organic Chemistry, Including
   Medicinal Chemistry. (Publications & Information Directorate, Council of
   Scientific and Industrial Research (CSIR), Hillside Rd., New Delhi 110 012,
   India)  V.14B-    1976-  Volume(issue)/page/year: 20,311,1981
 
                            *** END OF RECORD ***