*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : DL8250000
CHEMICAL NAME           : (1)Benzothieno(2,3-d)pyrimidine,
                          5,6,7,8-tetrahydro-4-(4-methyl-1-piperazinyl)-,
                          hydrochloride
CAS REGISTRY NUMBER     : 37724-43-9
LAST UPDATED            : 199007
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C15-H20-N4-S.Cl-H
MOLECULAR WEIGHT        : 324.91
WISWESSER LINE NOTATION : T B656 DN FN HS&&TJ C- AT6N DNTJ D1 &GH
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   *   4-(4-Methyl-1-piperazinyl)-5,6,7,8-tetrahydro-(1)benzothieno(2,3-d)pyrim
     idine hydrochloride
   * QM-1143
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 160 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   CHTPBA Chimica Therapeutica.  (Paris, France)  V.1-8, 1965-73.  For
   publisher information, see EJMCA5.  Volume(issue)/page/year: 7,224,1972
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 67 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   CHTPBA Chimica Therapeutica.  (Paris, France)  V.1-8, 1965-73.  For
   publisher information, see EJMCA5.  Volume(issue)/page/year: 7,224,1972
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 29 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   CHTPBA Chimica Therapeutica.  (Paris, France)  V.1-8, 1965-73.  For
   publisher information, see EJMCA5.  Volume(issue)/page/year: 7,224,1972
 
                            *** END OF RECORD ***