*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : DK9570000
CHEMICAL NAME           : 2H-1,2,4-Benzothiadiazine-7-sulfonamide,
                          6-chloro-3-methyl-, 1,1-dioxide
CAS REGISTRY NUMBER     : 1025-75-8
LAST UPDATED            : 199610
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C8-H8-Cl-N3-O4-S2
MOLECULAR WEIGHT        : 309.76
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 6-Chloro-3-methyl-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 100 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   IJPAAO Indian Journal of Pharmacy.  (Bombay, India)  V.1-40(1), 1939-78. For
   publisher information, see IJSIDW.  Volume(issue)/page/year: 27,3,1965
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 20 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   IJPAAO Indian Journal of Pharmacy.  (Bombay, India)  V.1-40(1), 1939-78. For
   publisher information, see IJSIDW.  Volume(issue)/page/year: 27,3,1965
 
                 ** OTHER MULTIPLE DOSE TOXICITY DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 30000 gm/kg/60D-C
TOXIC EFFECTS :
   Related to Chronic Data - death
REFERENCE :
   IJPAAO Indian Journal of Pharmacy.  (Bombay, India)  V.1-40(1), 1939-78. For
   publisher information, see IJSIDW.  Volume(issue)/page/year: 27,3,1965
 
                            *** END OF RECORD ***