*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : AH4080000
CHEMICAL NAME           : Acetic acid, (ethylenedinitrilo)tetra-, calcium (II)
                          complex
CAS REGISTRY NUMBER     : 12264-18-5
OTHER CAS REGISTRY NOS. : 1892-65-5
LAST UPDATED            : 199706
DATA ITEMS CITED        : 5
MOLECULAR FORMULA       : C10-H12-Ca-N2-O8.2H
MOLECULAR WEIGHT        : 330.34
WISWESSER LINE NOTATION : QV1N1VO&2N1VQ1VO &-CA-
COMPOUND DESCRIPTOR     : Reproductive Effector
SYNONYMS/TRADE NAMES :
   * Calciate(2-), ((ethylenedinitrilo)tetraacetato)-, dihydrogen
   * Calcium EDTA complex
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 9250 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   CRTXB2 CRC Critical Reviews in Toxicology.  (CRC Press, Inc., 2000 Corporate
   Blvd., NW, Boca Raton, FL 33431)  V.1-    1971- Volume(issue)/page/year:
   20,83,1989
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 573 mg(Ca)/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   PABIAQ Pathologie et Biologie.  (Paris, France)  V.1-16, 1953-68.  For
   publisher information, see PTBIAN.  Volume(issue)/page/year: 11,853,1963
 
                          ** REPRODUCTIVE DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 1344 mg/kg
SEX/DURATION            : female 11-15 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death,
   e.g., stunted fetus)
   Reproductive - Specific Developmental Abnormalities - musculoskeletal system
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   82,426,1986
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 2016 mg/kg
SEX/DURATION            : female 11-15 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Fertility - litter size (e.g. # fetuses per litter; measured
   before birth)
   Reproductive - Specific Developmental Abnormalities - skin and skin
   appendages
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   82,426,1986
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 2687 mg/kg
SEX/DURATION            : female 11-15 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Fertility - post-implantation mortality (e.g. dead and/or
   resorbed implants per total number of implants)
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   82,426,1986
 
                            *** END OF RECORD ***