*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : AH2525000
CHEMICAL NAME           : Acetic acid, diphenyl-,
                          2-(bis(2-hydroxyethyl)amino)ethyl ester,
                          hydrochloride
CAS REGISTRY NUMBER     : 1984-87-8
LAST UPDATED            : 199112
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C20-H25-N-O4.Cl-H
MOLECULAR WEIGHT        : 379.92
COMPOUND DESCRIPTOR     : Drug
                          Primary Irritant
SYNONYMS/TRADE NAMES :
   * N,N-Bis(2'-hydroxyethyl)aminoethyl diphenylacetate
   * Diphenylacetic acid 2-(bis(2-hydroxyethyl)amino)ethyl ester hydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                      ** SKIN/EYE IRRITATION DATA **
 
TYPE OF TEST            : Standard Draize test
ROUTE OF EXPOSURE       : Administration into the eye
SPECIES OBSERVED        : Mammal - cat
DOSE/DURATION           : 5%
REFERENCE :
   APPFAR Acta Poloniae Pharmaceutica (English Translation).  Translation of
   APPHAX.  (Warsaw, Poland) V.20-29, 1963-72.  Discontinued.
   Volume(issue)/page/year: 21,557,1964
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1380 mg/kg
TOXIC EFFECTS :
   Behavioral - changes in motor activity (specific assay)
   Behavioral - muscle contraction or spasticity
REFERENCE :
   APPFAR Acta Poloniae Pharmaceutica (English Translation).  Translation of
   APPHAX.  (Warsaw, Poland) V.20-29, 1963-72.  Discontinued.
   Volume(issue)/page/year: 21,557,1964
 
                            *** END OF RECORD ***