*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : AG9552000
CHEMICAL NAME : Acetic acid, ((2-(diethylamino)ethyl)thio)-,
6-ethenyldecahydro-5-hydroxy-4,6,9,10-
tetramethyl-1-oxo-3a,9-propano-3ah-cyclopentacyclooct
en-8-yl ester, (3aS-(3a-alpha,4-beta,
5-alpha,6-alpha,8-beta,9-beta,10S*))-
CAS REGISTRY NUMBER : 55297-95-5
OTHER CAS REGISTRY NOS. : 56142-71-3
BEILSTEIN REFERENCE NO. : 2229396
LAST UPDATED : 199806
DATA ITEMS CITED : 12
MOLECULAR FORMULA : C28-H47-N-O4-S
MOLECULAR WEIGHT : 493.82
WISWESSER LINE NOTATION : L569/FN 2AE N BVTJ H1 I1 JOV1S2N2&2 L1U1 L1 MQ N1
COMPOUND DESCRIPTOR : Drug
SYNONYMS/TRADE NAMES :
* 14-Deoxy-14-((2-diethylaminoethyl-thio)-acetoxy)mutiline
* Dynamutilin
* 81723 Hfu
* SQ 14055
* Thiamutilin
* Tiamulin
* Tiamulina
* Tiavet P
*** HEALTH HAZARD DATA ***
** ACUTE TOXICITY DATA **
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 2230 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
RZOVBM Rivista di Zootecnia e Veterinaria. Zootechnical and Veterinary
Review. (Rivista di Zootecni a e Veterinaria, Via le E. Bezzi 24, 201456
Milan, Italy) No.1- 1973- Volume(issue)/page/year: 8,251,1980
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Subcutaneous
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 4380 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
RZOVBM Rivista di Zootecnia e Veterinaria. Zootechnical and Veterinary
Review. (Rivista di Zootecni a e Veterinaria, Via le E. Bezzi 24, 201456
Milan, Italy) No.1- 1973- Volume(issue)/page/year: 8,251,1980
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 20 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
RZOVBM Rivista di Zootecnia e Veterinaria. Zootechnical and Veterinary
Review. (Rivista di Zootecni a e Veterinaria, Via le E. Bezzi 24, 201456
Milan, Italy) No.1- 1973- Volume(issue)/page/year: 8,251,1980
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 710 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
RZOVBM Rivista di Zootecnia e Veterinaria. Zootechnical and Veterinary
Review. (Rivista di Zootecni a e Veterinaria, Via le E. Bezzi 24, 201456
Milan, Italy) No.1- 1973- Volume(issue)/page/year: 8,251,1980
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Subcutaneous
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 1020 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
RZOVBM Rivista di Zootecnia e Veterinaria. Zootechnical and Veterinary
Review. (Rivista di Zootecni a e Veterinaria, Via le E. Bezzi 24, 201456
Milan, Italy) No.1- 1973- Volume(issue)/page/year: 8,251,1980
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 49 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
RZOVBM Rivista di Zootecnia e Veterinaria. Zootechnical and Veterinary
Review. (Rivista di Zootecni a e Veterinaria, Via le E. Bezzi 24, 201456
Milan, Italy) No.1- 1973- Volume(issue)/page/year: 8,251,1980
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Bird - chicken
DOSE/DURATION : 1550 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
RZOVBM Rivista di Zootecnia e Veterinaria. Zootechnical and Veterinary
Review. (Rivista di Zootecni a e Veterinaria, Via le E. Bezzi 24, 201456
Milan, Italy) No.1- 1973- Volume(issue)/page/year: 8,251,1980
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Bird - chicken
DOSE/DURATION : 25 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
RZOVBM Rivista di Zootecnia e Veterinaria. Zootechnical and Veterinary
Review. (Rivista di Zootecni a e Veterinaria, Via le E. Bezzi 24, 201456
Milan, Italy) No.1- 1973- Volume(issue)/page/year: 8,251,1980
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intramuscular
SPECIES OBSERVED : Bird - chicken
DOSE/DURATION : 250 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
RZOVBM Rivista di Zootecnia e Veterinaria. Zootechnical and Veterinary
Review. (Rivista di Zootecni a e Veterinaria, Via le E. Bezzi 24, 201456
Milan, Italy) No.1- 1973- Volume(issue)/page/year: 8,251,1980
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Bird - turkey
DOSE/DURATION : 1345 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
RZOVBM Rivista di Zootecnia e Veterinaria. Zootechnical and Veterinary
Review. (Rivista di Zootecni a e Veterinaria, Via le E. Bezzi 24, 201456
Milan, Italy) No.1- 1973- Volume(issue)/page/year: 8,251,1980
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intramuscular
SPECIES OBSERVED : Bird - turkey
DOSE/DURATION : 409 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
RZOVBM Rivista di Zootecnia e Veterinaria. Zootechnical and Veterinary
Review. (Rivista di Zootecni a e Veterinaria, Via le E. Bezzi 24, 201456
Milan, Italy) No.1- 1973- Volume(issue)/page/year: 8,251,1980
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Mammal - species unspecified
DOSE/DURATION : 812 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
DRFUD4 Drugs of the Future. (J.R. Prous, S.A., Apartado de Correos 540,
08080 Barcelona, Spain) V.1- 1975/76- Volume(issue)/page/year:
2,274,1977
*** END OF RECORD ***