*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : AF9537000
CHEMICAL NAME           : Acetic acid,
                          2-(7-chloro-1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-1,
                          4-benzodiazepin-3-yl) hydrazide
CAS REGISTRY NUMBER     : 84044-27-9
BEILSTEIN REFERENCE NO. : 5145064
LAST UPDATED            : 199612
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C18-H17-Cl-N4-O2
MOLECULAR WEIGHT        : 356.84
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   *   1-Methyl-7-chloro-5-phenyl-3-acetylhydrazino-2,3-dihydro-1H-1,4-benzodia
     zepin-2-one
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 700 mg/kg
TOXIC EFFECTS :
   Behavioral - anticonvulsant
   Behavioral - altered sleep time (including change in righting reflex)
   Behavioral - somnolence (general depressed activity)
REFERENCE :
   PCJOAU Pharmaceutical Chemistry Journal (English Translation).  Translation
   of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013)  No.1-
   1967-  Volume(issue)/page/year: 16,617,1982
 
                            *** END OF RECORD ***