*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : DK1660000
CHEMICAL NAME           : 2H-Benzo(a)quinolizine-3-carboxamide,
                          1,3,4,6,7,11b-hexahydro-2,2-bis(ethylthio)-N,N-diethy
                          l- 9,10-dimethoxy-, hydrochloride
CAS REGISTRY NUMBER     : 18065-97-9
LAST UPDATED            : 199007
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C24-H38-N2-O3-S2.Cl-H
MOLECULAR WEIGHT        : 503.22
WISWESSER LINE NOTATION : T B666 GNTT&J DS2 DS2 EVN2&2 LO1 MO1 &GH
COMPOUND DESCRIPTOR     : Drug
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 500 mg/kg
TOXIC EFFECTS :
   Brain and Coverings - recordings from specific areas of CNS
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 10,1183,1967
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 300 mg/kg
TOXIC EFFECTS :
   Brain and Coverings - recordings from specific areas of CNS
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 10,1183,1967
 
                            *** END OF RECORD ***