*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : DK1650000
CHEMICAL NAME           : 2H-Benzo(a)quinolizine-3-carboxamide,
                          N,N-diethyl-1,3,4,6,7,11b-hexahydro-2-hydroxy-9,10-
                          dimethoxy-, acetate (ester), hydrochloride
CAS REGISTRY NUMBER     : 113-69-9
LAST UPDATED            : 199504
DATA ITEMS CITED        : 4
MOLECULAR FORMULA       : C22-H32-N2-O5.Cl-H
MOLECULAR WEIGHT        : 441.02
WISWESSER LINE NOTATION : T B666 GNTT&J DOV1 EVN2&2 LO1 MO1 &GH
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 2-Acetoxy-3-diethylcarbamoyl-9,10-dimethoxyhexahydrobenzo(a)quinolizine  
   hydrochloride
   * Benzochinamide hydrochloride
   * Benzoquinamide hydrochloride
   * Benzquinamida clorhidrato
   * Benzquinamide hydrochloride
   * Emete-con
   * Emeticon
   * NSC 64375
   * P-2647 hydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 990 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   18,185,1971
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 580 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   MDACAP Medicamentos de Actualidad.  (J.R. Prous, S.A., Apartado de Correos
   540, 08080 Barcelona, Spain)  V.1-    1965-  Volume(issue)/page/year:
   11,9,1975
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 295 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   MDACAP Medicamentos de Actualidad.  (J.R. Prous, S.A., Apartado de Correos
   540, 08080 Barcelona, Spain)  V.1-    1965-  Volume(issue)/page/year:
   11,9,1975

         *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
   NOES - National Occupational Exposure Survey (1983)
     NOES Hazard Code - X5619
       No. of Facilities: 106 (estimated)
       No. of Industries: 1
       No. of Occupations: 2
       No. of Employees: 6572 (estimated)
       No. of Female Employees: 6249 (estimated)

 
                            *** END OF RECORD ***