*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : DJ4990500
CHEMICAL NAME           : Benzo(e)pyrene, 4,5-dihydro-4,5-dihydroxy-
CAS REGISTRY NUMBER     : 24961-49-7
LAST UPDATED            : 199803
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C20-H14-O2
MOLECULAR WEIGHT        : 286.34
COMPOUND DESCRIPTOR     : Tumorigen
                          Mutagen
SYNONYMS/TRADE NAMES :
   * Benzo(e)pyrene-4,5-dihydrodiol
   * B(e)P 4,5-dihydrodiol
   * trans-4,5-Dihydroxy-4,5-dihydrobenzo(e)pyrene
 
                       *** HEALTH HAZARD DATA ***
 
                          ** TUMORIGENIC DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 32 mg/kg/15D-I
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Lungs, Thorax, or Respiration - tumors
   Liver - tumors
REFERENCE :
   CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
   Sts., Philadelphia, PA 19106)  V.1-    1941-  Volume(issue)/page/year:
   40,203,1980
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 10 nmol/plate
REFERENCE :
   JBCHA3 Journal of Biological Chemistry.  (428 E. Preston St., Baltimore, MD
   21202)  V.1-    1905-  Volume(issue)/page/year: 254,4408,1979
 
                            *** END OF RECORD ***