*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : DJ2981770
CHEMICAL NAME           : 4H-1-Benzopyran-4-one,
                          2,3-dihydro-2-(2,3-dihydro-3-(4-hydroxy-3-methoxyphen
                          yl)-2-
                          (hydroxymethyl)-1,4-benzodioxin-6-yl)-3,5,7-trihydrox
                          y-, (2R-(2-alpha,3-beta,6(2R*,3R*)))-
CAS REGISTRY NUMBER     : 22888-70-6
LAST UPDATED            : 199506
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C25-H22-O10
MOLECULAR WEIGHT        : 482.47
COMPOUND DESCRIPTOR     : Drug
                          Natural Product
SYNONYMS/TRADE NAMES :
   * 7C3MT
   * Flavobin
   * Flavobin Spofa
   * Silibinin
   * Silliver
   * Silybin
   * Silybine
   * Silymarine I
   * Silymarin I
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1056 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   YHTPAD Yaoxue Tongbao. Bulletin of Pharmacology. (China International Book
   Trading Corp., POB 2820, Beijing, Peop. Rep. China) V.13-23,    1978-88. For
   publisher information, see ZYZAEU.  Volume(issue)/page/year: 18,404,1983
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Unreported
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 300 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   YHTPAD Yaoxue Tongbao. Bulletin of Pharmacology. (China International Book
   Trading Corp., POB 2820, Beijing, Peop. Rep. China) V.13-23,    1978-88. For
   publisher information, see ZYZAEU.  Volume(issue)/page/year: 18,404,1983
 
                            *** END OF RECORD ***