*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : DJ2830000
CHEMICAL NAME           : 2H-1-Benzopyrano(5',6':6,7)indeno(1,2-b)indol-3(4bh)-
                          one, 5,6,6a,7,12,12b,12c,13,14,14a-
                          decahydro-4b-hydroxy-2-(1-hydroxy-1-methylethyl)-12b,
                          12c-dimethyl-, (2-alpha,4b-beta,6a-
                          alpha,12b-beta,12c-alpha,14a-beta)-
CAS REGISTRY NUMBER     : 57186-25-1
BEILSTEIN REFERENCE NO. : 5317894
LAST UPDATED            : 199612
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C27-H33-N-O4
MOLECULAR WEIGHT        : 435.61
COMPOUND DESCRIPTOR     : Natural Product
SYNONYMS/TRADE NAMES :
   * Paxilline
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD - Lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >227 mg/kg
TOXIC EFFECTS :
   Behavioral - tremor
REFERENCE :
   JANTAJ Journal of Antibiotics.  (Japan Antibiotics Research Assoc., 2-20-8
   Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan)  V.2-5, 1948-52;  V.21- 1968-
   Volume(issue)/page/year: 41,1868,1988
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Unreported
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 150 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   41KEAL "Toxicology, Biochemistry and Pathology of Mycotoxins," Uraguchi, K.
   and M. Yamazaki, eds., New York, John Wiley & Sons, Inc., 1978
   Volume(issue)/page/year: -,108,1978
 
TYPE OF TEST            : LD - Lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Bird - chicken
DOSE/DURATION           : >100 mg/kg
TOXIC EFFECTS :
   Behavioral - tremor
REFERENCE :
   JANTAJ Journal of Antibiotics.  (Japan Antibiotics Research Assoc., 2-20-8
   Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan)  V.2-5, 1948-52;  V.21- 1968-
   Volume(issue)/page/year: 41,1868,1988
 
                            *** END OF RECORD ***