*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : DJ2253000
CHEMICAL NAME           : 2H-1-Benzopyran-3-carboxamide, N,N-diethyl-2-oxo-
CAS REGISTRY NUMBER     : 18144-62-2
BEILSTEIN REFERENCE NO. : 0216665
REFERENCE               : 4-18-00-05572 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C14-H15-N-O3
MOLECULAR WEIGHT        : 245.30
WISWESSER LINE NOTATION : T66 BOVJ DVN2&2
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Coumarin-3-carboxylic acid diethylamide
   * N,N-Diethyl-2-oxo-2H-1-benzopyran-3-carboxamide
   * N,N-Diethyl-3-coumarincarboxamide
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 790 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - changes in motor activity (specific assay)
   Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
   APFRAD Annales Pharmaceutiques Francaises.  (SPPIF, B.P.22, F-41353 Vineuil,
   France)  V.1-    1943-  Volume(issue)/page/year: 22,131,1964
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 586 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   YKKZAJ Yakugaku Zasshi.  Journal of Pharmacy.  (Nippon Yakugakkai, 2-12-15
   Shibuya, Shibuya-ku, Tokyo 150, Japan)  No.1-    1881-
   Volume(issue)/page/year: 71,686,1951
 
                            *** END OF RECORD ***