*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : DI8535000
CHEMICAL NAME           : Benzo(c)phenanthrene-3,4-diol,
                          1,2,3,4-tetrahydro-1,2-epoxy-, (E)-(-)-(1R,2S,3S,4R)-
CAS REGISTRY NUMBER     : 82510-57-4
LAST UPDATED            : 199706
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C18-H14-O3
MOLECULAR WEIGHT        : 278.32
COMPOUND DESCRIPTOR     : Tumorigen
SYNONYMS/TRADE NAMES :
   * (-)-Benzo(c)phenanthrene-3,4-diol-1,2-epoxide-2
   *   trans-1-beta,2-beta-Epoxy-1,2,3,4-tetrahydrobenzo(c)phenanthrene-3-beta,
     4-alpha-diol
 
                       *** HEALTH HAZARD DATA ***
 
                          ** TUMORIGENIC DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 111 ug/kg
TOXIC EFFECTS :
   Tumorigenic - neoplastic by RTECS criteria
   Skin and Appendages - tumors
REFERENCE :
   CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
   Sts., Philadelphia, PA 19106)  V.1-    1941-  Volume(issue)/page/year:
   46,2257,1986
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 12 mg/kg/15D-I
TOXIC EFFECTS :
   Tumorigenic - neoplastic by RTECS criteria
   Liver - tumors
REFERENCE :
   CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
   Sts., Philadelphia, PA 19106)  V.1-    1941-  Volume(issue)/page/year:
   46,2257,1986
 
                            *** END OF RECORD ***