*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : DI2366000
CHEMICAL NAME           : Benzo(b)-1,5-naphthyridin-10-amine,
                          7-chloro-N-(2-(2-((2-chloroethyl)ethylamino)ethoxy)
                          ethyl)-2-methoxy-, dihydrochloride
CAS REGISTRY NUMBER     : 38915-33-2
LAST UPDATED            : 199410
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C21-H26-Cl2-N4-O2.2Cl-H
MOLECULAR WEIGHT        : 510.33
WISWESSER LINE NOTATION : T C666 BN GNJ FO1 IM2O2N2&2G MG &GH 2
COMPOUND DESCRIPTOR     : Drug
                          Mutagen
SYNONYMS/TRADE NAMES :
   * ICR 415
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD20 - Lethal Dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1 mg/kg
TOXIC EFFECTS :
   Tumorigenic - active as anti-cancer agent
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 15,739,1972
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 5 ug/plate
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 15,739,1972
 
                            *** END OF RECORD ***