*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : DI2240000
CHEMICAL NAME           : 6H-Benzo(d)naphtho(1,2-b)pyran-6-one,
                          4-(6-deoxy-alpha-galactofuranosyl)-8-ethenyl-
                          1-hydroxy-10,12-dimethoxy-
CAS REGISTRY NUMBER     : 77879-90-4
LAST UPDATED            : 199706
DATA ITEMS CITED        : 4
MOLECULAR FORMULA       : C27-H26-O9
MOLECULAR WEIGHT        : 494.53
WISWESSER LINE NOTATION : T E6 B666 COVJ G1U1 IO1 MO1 OQ R- BT5OTJ CQ DQ EYQ1
COMPOUND DESCRIPTOR     : Mutagen
                          Natural Product
SYNONYMS/TRADE NAMES :
   * DC-38-V
   * Gilvocarcin V
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD - Lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >1 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JANTAJ Journal of Antibiotics.  (Japan Antibiotics Research Assoc., 2-20-8
   Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan)  V.2-5, 1948-52;  V.21- 1968-
   Volume(issue)/page/year: 34,266,1981
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 300 mg/kg
TOXIC EFFECTS :
   Tumorigenic - active as anti-cancer agent
REFERENCE :
   JANTAJ Journal of Antibiotics.  (Japan Antibiotics Research Assoc., 2-20-8
   Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan)  V.2-5, 1948-52;  V.21- 1968-
   Volume(issue)/page/year: 34,266,1981
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : DNA inhibition
TEST SYSTEM             : Bacteria - Bacillus subtilis
DOSE/DURATION           : 500 ug/L
REFERENCE :
   JANTAJ Journal of Antibiotics.  (Japan Antibiotics Research Assoc., 2-20-8
   Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan)  V.2-5, 1948-52;  V.21- 1968-
   Volume(issue)/page/year: 35,545,1982
 
TYPE OF TEST            : Mutation test systems - not otherwise specified
TEST SYSTEM             : Bacteria - Bacillus subtilis
DOSE/DURATION           : 500 ug/L
REFERENCE :
   JANTAJ Journal of Antibiotics.  (Japan Antibiotics Research Assoc., 2-20-8
   Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan)  V.2-5, 1948-52;  V.21- 1968-
   Volume(issue)/page/year: 35,545,1982
 
                            *** END OF RECORD ***