*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : DI0876700
CHEMICAL NAME           : Benzoic acid, 3,4,5-trimethoxy-,
                          4-(4-phenyl-1-piperazinyl)butyl ester,
                          dihydrochloride
CAS REGISTRY NUMBER     : 5914-66-9
LAST UPDATED            : 199712
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C24-H32-N2-O5.2Cl-H
MOLECULAR WEIGHT        : 501.50
SYNONYMS/TRADE NAMES :
   * MA 568
   * 4-(4-Phenyl-1-piperazinyl)butyl 3,4,5-trimethoxybenzoate dihydrochloride
   * 3,4,5-Trimethoxybenzoic acid 4-(4-phenyl-1-piperazinyl)butyl ester  
   dihydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 2500 mg/kg
TOXIC EFFECTS :
   Behavioral - altered sleep time (including change in righting reflex)
   Behavioral - changes in motor activity (specific assay)
   Behavioral - antipsychotic
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 6,133,1963
 
                            *** END OF RECORD ***