*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : DH6832500
CHEMICAL NAME           : Benzoic acid,
                          2-(2,4,5,7-tetrabromo-6-hydroxy-3-oxo-3H-xanthen-9-yl
                          )-, disodium salt
CAS REGISTRY NUMBER     : 548-26-5
LAST UPDATED            : 199710
DATA ITEMS CITED        : 6
MOLECULAR FORMULA       : C20-H8-Br4-O5.2Na
MOLECULAR WEIGHT        : 693.90
COMPOUND DESCRIPTOR     : Tumorigen
                          Mutagen
SYNONYMS/TRADE NAMES :
   * Aizen eosine GH
   * Bromo acid
   * Bromo B
   * Bromo 4D
   * Bromo 4DC
   * Bromo 4DL
   * Bromoeosine
   * Bromo FL
   * Bromofluoresceic acid
   * Bromo Fluorescein
   * Bromo JPS
   * Bromo TS
   * Bromo X-100
   * Bromo XX
   * Bronze Bromo
   * Certiqual Eosine
   * C.I. 45380
   * C.I. Acid Red 87
   * Eosin
   * Eosine B
   * Eosine BPC
   * Eosine BS
   * Eosine BS-SF
   * Eosine DA
   * Eosine DWC 73
   * Eosine Extra Conc. A. Export
   * Eosine FA
   * Eosine 3G
   * Eosine GF
   * Eosine J
   * Eosine K Salt Free
   * Eosine Lake Red Y
   * Eosine Salt Free
   * Eosine w/s
   * Eosine YB
   * Eosine YS
   * Eosin Y
   * Eosin YS
   * Fenazo eosine XG
   * Fluorescein, 2',4',5',7'-tetrabromo-, disodium salt
   * Hidacid Boiling Bromo
   * Hidacid Bromo acid regular
   * Hidacid Dibromo Fluorescein
   * Hidacid Eosine Soda Salt
   * Hidacid White Bromo
   * Irgalite Bronze Red CL
   * Phloxine Red 20-7600
   * 11445 Red
   * 11731 Red
   * Sodium eosine
   * Symuler Eosin Toner
   * Tetrabromofluorescein D
   * Tetrabromofluorescein S
   * Tetrabromofluorescein soluble
   * Toyo Eosine G
   * 1903 Yellow Pink
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 550 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   44,225,1978
 
                          ** TUMORIGENIC DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 13 gm/kg/1Y-I
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Skin and Appendages - tumors
   Tumorigenic - tumors at site of application
REFERENCE :
   GANNA2 Gann.  Japanese Journal of Cancer Research.  (Tokyo, Japan)  V.1-75,
   1907-84.  For publisher information, see JJCREP.  Volume(issue)/page/year:
   47,51,1956

         *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
   NOHS - National Occupational Hazard Survey (1974)
     NOHS Hazard Code - 82264
       No. of Facilities: 106 (estimated)
       No. of Industries: 1
       No. of Occupations: 3
       No. of Employees: 293 (estimated)

                          *** STATUS IN U.S. ***
 
   EPA GENETOX PROGRAM 1988, Negative: S cerevisiae gene conversion
   
   EPA GENETOX PROGRAM 1988, Inconclusive: B subtilis rec assay
   
   EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JUNE 1998

 
                            *** END OF RECORD ***