*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : DH6825000
CHEMICAL NAME           : Benzoic acid, o-sulfamoyl-, isopropyl ester
CAS REGISTRY NUMBER     : 14065-41-9
BEILSTEIN REFERENCE NO. : 2809544
LAST UPDATED            : 199612
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C10-H13-N-O4-S
MOLECULAR WEIGHT        : 243.30
WISWESSER LINE NOTATION : ZSWR BVOY1&1
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Isopropyl ester of o-sulfamoyl-benzoic acid
   * SKF 7711
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1690 mg/kg
TOXIC EFFECTS :
   Behavioral - ataxia
   Behavioral - rigidity (including catalepsy)
REFERENCE :
   AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
   Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium)  V.4-   
   1898-  Volume(issue)/page/year: 168,220,1967
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 390 mg/kg
TOXIC EFFECTS :
   Behavioral - anticonvulsant
   Behavioral - changes in motor activity (specific assay)
REFERENCE :
   PCJOAU Pharmaceutical Chemistry Journal (English Translation).  Translation
   of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013)  No.1-
   1967-  Volume(issue)/page/year: 14,94,1980
 
                            *** END OF RECORD ***