*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : DH2186000
CHEMICAL NAME           : Benzoic acid, p-hydroxy-, ester with
                          (3-hydroxypropyl)guanidine, monohydrochloride
CAS REGISTRY NUMBER     : 19623-22-4
LAST UPDATED            : 198612
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C11-H15-N3-O3.Cl-H
MOLECULAR WEIGHT        : 273.75
WISWESSER LINE NOTATION : QR DVO3MYZUM &GH
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * HM-203
   * p-Hydroxybenzoic acid ester with (3-hydroxypropyl)guanidine hydrochloride
   * 3-(p-Hydroxy-benzoyloxy)propylguanidine hydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 100 mg/kg
TOXIC EFFECTS :
   Peripheral Nerve and Sensation - flaccid paralysis without anesthesia
   (usually neuromuscular blockage)
   Behavioral - somnolence (general depressed activity)
   Behavioral - convulsions or effect on seizure threshold
REFERENCE :
   AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
   Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium)  V.4-   
   1898-  Volume(issue)/page/year: 175,193,1968
 
                            *** END OF RECORD ***